大手製薬会社での核酸医薬DDS博士研究員の求人
求人ID:133595
募集終了
転職求人情報
職種
核酸医薬DDS博士研究員
ポジション
担当者
おすすめ年齢
20代
30代
40代
50代以上
年収イメージ
応相談(経験・能力を考慮の上当社規定により決定)
仕事内容
[Accountabilities]
●This position is accountable for hypothesis generation, research planning and execution of cutting edge DDS research of ASO delivery by effectively communicating with research partners. In addition, search and evaluation of external technologies are also included in the role.
●The research covers mechanism of action study via various cells including iPSC, immunohistochemical staining, protein binding analysis, and others.
●This position is also accountable for reporting and writing research progress timely to one’s supervisor.
[Goal]
Oligonucleotide therapeutics such as antisense oligonucleotides (ASOs) is a promising drug platform for the treatment of neurological diseases. ASOs expand the set of druggable targets, which small-molecules and mAbs cannot access. However, currently oligonucleotides must be administered directly into the cerebral spinal fluid by invasive intrathecal administration to deliver inside the brain. Systemic administration with a novel DDS (drug delivery system) which could transfer ASO to the brain from blood represents many clinical benefits to patients. Our goal is to discover novel DDS which allow systemic administration of ASO to deliver into the brain.
●This position is accountable for hypothesis generation, research planning and execution of cutting edge DDS research of ASO delivery by effectively communicating with research partners. In addition, search and evaluation of external technologies are also included in the role.
●The research covers mechanism of action study via various cells including iPSC, immunohistochemical staining, protein binding analysis, and others.
●This position is also accountable for reporting and writing research progress timely to one’s supervisor.
[Goal]
Oligonucleotide therapeutics such as antisense oligonucleotides (ASOs) is a promising drug platform for the treatment of neurological diseases. ASOs expand the set of druggable targets, which small-molecules and mAbs cannot access. However, currently oligonucleotides must be administered directly into the cerebral spinal fluid by invasive intrathecal administration to deliver inside the brain. Systemic administration with a novel DDS (drug delivery system) which could transfer ASO to the brain from blood represents many clinical benefits to patients. Our goal is to discover novel DDS which allow systemic administration of ASO to deliver into the brain.
必要スキル
[Requirements]
Required:
●Good verbal and written communication skills in Japanese and/or English to work productively as a research team
●Proactive mindset to effectively drive collaborative researches forward with internal and external partners
●PhD or equivalent in cell biology, drug delivery, pharmacokinetics or related field
●Research experience in the field of blood-brain barrier or oligonucleotide DDS
Preferred:
□Knowledge and expertise of drug discovery in the field of central nervous system diseases, pharmacokinetics, or safety.
□Research experience of immunohistochemical staining, genetic analysis, proteomics
□Experience of collaborative research with external partner.
Required:
●Good verbal and written communication skills in Japanese and/or English to work productively as a research team
●Proactive mindset to effectively drive collaborative researches forward with internal and external partners
●PhD or equivalent in cell biology, drug delivery, pharmacokinetics or related field
●Research experience in the field of blood-brain barrier or oligonucleotide DDS
Preferred:
□Knowledge and expertise of drug discovery in the field of central nervous system diseases, pharmacokinetics, or safety.
□Research experience of immunohistochemical staining, genetic analysis, proteomics
□Experience of collaborative research with external partner.
就業場所
就業形態
正社員
企業名
国内トップ製薬メーカー。
企業概要
国内首位の製薬メーカー。世界のグローバルトップ10を目指す。
生活習慣病に強み。米国社買収でがん領域強化。新興国開拓へスイス大手買収。
生活習慣病に強み。米国社買収でがん領域強化。新興国開拓へスイス大手買収。
企業PR
業務カテゴリ
組織カテゴリ
備考
その他(事業会社)の求人情報
事業会社の求人情報
メーカーの求人情報
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